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Are There Thresholds for Non-genotoxic and Genotoxic Carcinogens?

Are There Thresholds for Non-genotoxic and Genotoxic Carcinogens?

2018-01-03
A carcinogen is a substance or agent capable of causing cancer. A carcinogen can be furthe Read More.

Skin Sensitization Tests and GHS Classification Criteria

Skin Sensitization Tests and GHS Classification Criteria

2017-11-08
A chemical substance will be classified as a skin sensitizer if there is reliable human ev Read More.

GHS: Factors to Consider When Classifying A Substance as A Specific Target Organ Toxicant

GHS: Factors to Consider When Classifying A Substance as A Specific Target Organ Toxicant

2017-05-26
A substance will be classified as a Specific Target Organ Toxicant (STOT) if it produces s Read More.

What Is Point of Departure (POD) and How to Use It to Calculate Toxicological Reference Dose (RfD)

What Is Point of Departure (POD) and How to Use It to Calculate Toxicological Reference Dose (RfD)

2017-04-06
In toxicology, point of departure (POD) is defined as the point on a toxicological do Read More.

How to Use ECETOC TRA Tool Part II: Consumer Exposure Estimation and Health Risk Assessment

How to Use ECETOC TRA Tool Part II: Consumer Exposure Estimation and Health Risk Assessment

2017-02-09
Consumers may be directly or indirectly exposed to certain chemical substances from the pr Read More.

How to Use ECETOC TRA Tool Part I: Worker Health Risk Assessment

How to Use ECETOC TRA Tool Part I: Worker Health Risk Assessment

2016-12-19
ECETOC's Targeted Risk Assessment  tool (ECETOC TRA) is a free tool developed by the  Read More.

How to Calculate Derived Minimal Effect Level (DMEL)

How to Calculate Derived Minimal Effect Level (DMEL)

2016-09-04
Derived minimal effect level (DMEL)  is defined as a level of exposure below whi Read More.

How to Modify Dose Descriptors to A Correct Starting Point

How to Modify Dose Descriptors to A Correct Starting Point

2016-08-10
When calculating derived no-effect level (DNEL), it is very important to convert certain&n Read More.

Overview of Toxicological Dose Descriptors (LD50, LC50, EC50, NOAEL, LOAEL, etc)

Overview of Toxicological Dose Descriptors (LD50, LC50, EC50, NOAEL, LOAEL, etc)

2016-06-17
In toxicology and eco-toxicology, dose descriptor is the term used to identify the relatio Read More.

How to Derive Derived No-Effect Level (DNEL)

How to Derive Derived No-Effect Level (DNEL)

2016-06-14
Derived No-Effect Level (DNEL) is defined as the level of chemical exposure above whi Read More.

Toxicokinetics

Toxicokinetics

2016-04-26
Toxicokinetics(TK) is essentially the study of how a substance gets into the body and Read More.

Carcinogenicity

Carcinogenicity

2016-04-26
A carcinogen is a chemical substance or a mixture of chemical substances that induces canc Read More.

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